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hy 147007  (MedChemExpress)


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    Structured Review

    MedChemExpress hy 147007
    Hy 147007, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 3 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/hy+147007/%CE%B2-catenin-IN-3/pmc12903609-87-85-86
    Average 94 stars, based on 3 article reviews
    hy 147007 - by Bioz Stars, 2026-09
    94/100 stars

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    In Vitro:

    Article Title: The promoting roles of GLP1R and GIPR in stemness maintenance and multiple lineage-specific differentiation of PDLSCs
    Article Snippet: .. The in vitro treatment conditions for the small-molecule compound were as follows: GLP1RA semaglutide acetate (10 nM, 24 h), GIPRA (Pro3) GIP (0.5 nM, 24 h), GLP-1R/GIPR agonist-1 (10 nM, 24 h) also termed as 2GRA in this study, BGM0504 (2 nM, 24 h, BrightGene Pharmaceutical Co., Ltd., China) [ ], CREB inhibitor 666-15 (1 μM, 2 h, HY-101120, MCE), Akt inhibitor MK-2206 (5 μM, 24 h, HY-108232, MCE), ERK1/2 inhibitor SCH772984 (0.5 μM, 24 h, HY-50846, MCE), β-catenin inhibitor IN-3 (5 μM, 24 h, HY-147007, MCE), STAT3-IN-14 (5 μM, 2 h, HY-N10472, MCE). .. PDLSCs were induced to differentiate into osteogenic (HUXXC-90021, OriCell, China), adipogenic (HUXXC-90031, OriCell), and chondrogenic (HUXXC-90041, OriCell) lineages using commercial differentiation kits according to the manufacturer’s protocols.

    Article Title: The promoting roles of GLP1R and GIPR in stemness maintenance and multiple lineage-specific differentiation of PDLSCs.
    Article Snippet: .. The in vitro treatment conditions for the small-molecule compound were as follows: GLP1RA semaglutide acetate (10 nM, 24 h), GIPRA (Pro3) GIP (0.5 nM, 24 h), GLP1R/GIPR agonist-1 (10 nM, 24 h) also termed as 2GRA in this study, BGM0504 (2 nM, 24 h, BrightGene Pharmaceutical Co., Ltd., China) [13], CREB inhibitor 666-15 (1 μM, 2 h, HY-101120, MCE), Akt inhibitor MK-2206 (5 μM, 24 h, HY-108232, MCE), ERK1/2 inhibitor SCH772984 (0.5 μM, 24 h, HY-50846, MCE), β-catenin inhibitor IN-3 (5 μM, 24 h, HY-147007, MCE), STAT3-IN-14 (5 μM, 2 h, HY-N10472, MCE). .. PDLSCs were induced to differentiate into osteogenic (HUXXC-90021, OriCell, China), adipogenic (HUXXC-90031, OriCell), and chondrogenic (HUXXC-90041, OriCell) lineages using commercial differentiation kits according to the manufacturer’s protocols.



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